Bismuth nanoparticles against microbial infections

Nanomedicine (Lond). 2022 Nov;17(27):2109-2122. doi: 10.2217/nnm-2022-0153. Epub 2023 Feb 14.

Abstract

The destructive effect of infectious diseases on human life and the emergence of antibiotic-resistant strains highlight the importance of developing new and appropriate treatment strategies, one of which is the use of metals as therapeutic agents. Bismuth nanoparticles are an example of prominent metal-containing drugs. The therapeutic effects of bismuth-based drugs in the treatment of wounds have been proven. Various laboratory studies have confirmed the antimicrobial effects of bismuth nanoparticles, including the clinical treatment of ulcers caused by Helicobacter pylori. Therefore, considering the performance of this nanoparticle and its potent effect on infectious agents and its therapeutic dimensions, the present study fully investigated the properties and performance of this metal-based nanoparticle.

Keywords: BiNPs; antibacterial treatment; antibiotics; bismuth; nanoparticles.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Bismuth / therapeutic use
  • Helicobacter Infections* / drug therapy
  • Helicobacter pylori*
  • Humans
  • Metal Nanoparticles* / therapeutic use

Substances

  • Bismuth
  • Anti-Bacterial Agents